Antigen Production
-
Peptide-specific Antibody Production
We offer the full process: From finding the best peptide sequences for antibody production to ready-to-use purified antibodies. Both polyclonal and monoclonal antibodies can be made this way.
-
Modified Peptides as Antigen
Would you like an antibody that specifically recognizes a post-translational modification at a given point in your protein? We can help you achieve this.
-
Recombinant Protein Production
We offer gene synthesis and transient gene expression for the production of recombinant proteins in eukaryote or prokaryote cells.
Antigen Production
Protein as an Antigen
Would you like to use a peptide-conjugate, a whole protein or a subunit as antigen? If you don’t have the protein in-house, we can make it for you. We also have extensive experience in making antigens for phospho-specific or acytelation-specific antibody development. We use the following techniques for antigen development:
Peptide synthesis and conjugation
The most popular way of generating an antigen today is by peptide synthesis and conjugation to carrier protein for peptide-specific antibodies. We can help you pin-point areas of the the protein that is suitable for antibody generation, using our peptide design service.
Recombinant protein generation
We can offer gene synthesis and transient gene expression for the production of recombinant proteins in eukaryote or prokaryote cells.
Fab2 or Fab fragment generation
When making an anti-drug antibody assay, antibodies specific to the variable regions of your antibody need to be generated. We can assist you with generating and purifying Fab2 or Fab fragments of antibodies. The purified Fab-fragments will be used as antigen to generate antiserum, which in turn can be affinity purified for your assay.
What makes us different
-
Capra Science Organic Farm is located in southern Sweden.
We are proud to say that Swedish authorities have some of the strictest regulations worldwide for animal keeping, ethics and the environment.
In addition we have chosen to be ISO 9001 as well as organically certified. Our farm is certified organic since many years back and has been awarded multiple times for outstanding animal care.
-
Our top priority is to promote healthy animals with strong immune systems.
A strong immune system will give substantially higher levels of antigen-specific antibodies in serum upon an antigen challenge.
-
We have developed unique and gentle immunization programs. The programs are adapted to each host and optimized for a generous production of antigen-specific antibodies.
-
The entire chain of events in antibody production and downstream processes take place onsite. We have a purpose-build organic farm as well as laboratories. We don't work with subcontractors. This guarantees a high level of quality assurance and IP security.
Top 7 reasons to work with us
Expertise. Our advanced laboratory, in-depth knowledge and robust protocols guarantee the best performing antibodies. The antibody expertise of our staff will be within your reach throughout your project.
Discretion. Your project is safe with us. The whole chain of events in your antibody production and downstream processes are done at Capra Science’s own farm and laboratories with no subcontractors.
Quality. Capra Science holds an ISO 9001 quality assurance to guarantee top product quality.
Cost-efficiency. Our unique animal care program has been optimized to yield a high titer antiserum.
Ethical standards. Animal welfare is our top priority. We run 1st class award-winning animal care facilities at our purpose-built organic farm.
Flexibility. Your antibody production is customized to meet your specific needs.
Personal service. A project with us includes free expert email consultation throughout your antibody production. We enjoy the personal contact with every client. Our scientific curiosity and nerdy ambition to continuously learn and improve, make us good listeners and allow us to deliver exactly what you need.