Hen Antibody Production

Polyclonal antibody production of IgY from egg yolks of hens make valuable antibodies for R&D and diagnostics. Especially, for evolutionary conserved mammalian antigen sequences, using hens are an advantage. Another benefit is their remarkable egg-laying capacity, enabling large-batches of antibodies to be produced from a only a few individuals.

Our standard immunization program which can be adjusted to your specific needs of antibody generation. The entire chain of actions are carried out at our purpose built organic farm and onsite laboratory facilities.

  • Our White Leghorn and Brown Lohmann chickens are well suited for the purpose of antibody production and lay approximately 300 eggs/year. The IgY is normally shipped to the customer as purified total IgY or affinity purified antibodies.  

  • In our polyclonal chicken egg IgY antibody service, the standard schedule starts with a 10-week immunizing scheme, with the freedom to continue IgY production thereafter.

    • when you need a small or a large production of antibodies

    • when you need to perform pilot studies

    • when your antigen is highly conserved among species.

    •  when most of your antibodies are made in rabbit. Choosing hen IgY will allow you to perform double immunostainings

    • when you have a small budget

    • if you want to use the antibody in vivo, as IgY does not activate mammalian complement systems

    • when there are advantages in using antibodies lacking the "Fc domain". IgY do not bind to mammalian Fc receptors. The mammalian Fc domain also binds "rheumatoid factors". 

    • Antibodies for pilot studies

    • Custom Antibodies for core research

    • Diagnostic antibody development

    • ELISA assays (direct, in-direct, Sandwich)

    • Immunohistochemistry

    • Immunoprecipitation (IP or Co-IP)

    • Polyclonal Antibody Development for R&D experiments

    • Peptide-specific antibody development

    • Pull-down assays

    • Site-specific antibody development

    • Western Blot

    • Antigen design – consultation

    • Peptide design by our experts

    • Peptide synthesis and conjugation

    • Recombinant antigen generation

    • DNA-contruct design for DNA immunization

    • Antigen-specific affinity purification

    • IgY-purification

    • Target-validation by ELISA (QC-ELISA)

    • Target-validation: ELISAs (in-direct, sandwich, competitive), SDS_PAGE, Western blot

    • Antibody assay development

    • Antibody labeling (e.g. HRP, Flourescence, AP)

    • 1st class award-winning animal care on our organic farm

    • Legal ethical approval and approved animal facilities.

    • High-quality laboratory work and robust protocols

    • Quality assurance system in place

    • High IP-security on one-site producing unit

What makes us different

  • Capra Science Organic Farm is located in southern Sweden.

    We are proud to say that Swedish authorities have some of the strictest regulations worldwide for animal keeping, ethics and the environment.

    In addition we have chosen to be ISO 9001 as well as organically certified. Our farm is certified organic since many years back and has been awarded multiple times for outstanding animal care.

  • Our top priority is to promote healthy animals with strong immune systems.

    A strong immune system will give substantially higher levels of antigen-specific antibodies in serum upon an antigen challenge. 

  • We have developed unique and gentle immunization programs. The programs are adapted to each host and optimized for a generous production of antigen-specific antibodies.

  • The entire chain of events in antibody production and downstream processes take place onsite. We have a purpose-built organic farm as well as laboratories. We don't work with subcontractors. This guarantees a high level of quality assurance and IP security.

Meet our hens

Top 7 reasons to work with us

  1. Expertise. Our advanced laboratory, in-depth knowledge and robust protocols guarantee the best performing antibodies. The antibody expertise of our staff will be within your reach throughout your project.

  2. Discretion. Your project is safe with us. The whole chain of events in your antibody production and downstream processes are done at Capra Science’s own farm and laboratories with no subcontractors.

  3. Quality. Capra Science holds an ISO 9001 quality assurance to guarantee top product quality.

  4. Cost-efficiency. Our unique animal care program has been optimized to yield a high titer antiserum.

  5. Ethical standards. Animal welfare is our top priority. We run 1st class award-winning animal care facilities at our purpose-built organic farm.

  6. Flexibility. Your antibody production is customized to meet your specific needs.

  7. Personal service. A project with us includes free expert email consultation throughout your antibody production. We enjoy the personal contact with every client. Our scientific curiosity and nerdy ambition to continuously learn and improve, make us good listeners and allow us to deliver exactly what you need.