MONOCLONAL ANTIBODY PRODUCTION / NANOBODY PRODUCTION

Nanobody Production

Antibody production in alpaca has become a popular service. This is due to the animal's unique ability to generate single-chain antibodies (nanobodies).

We assist R&D-units of companies in generating drug candidates for their next generation of life-saving biological pharmaceuticals.

Starting from antigen, we deliver target-validated recombinant singel-chain VHH drug candidates. For your IP-safety, the entire chain of actions are carried out at our purpose-built organic farm and onsite laboratory facilities.

  • Capra Science mild and effectiv immunization program for alpacas include all steps necessary to generate a successful immune response for downstream activities of securing top performing monoclonal nanobody candidates.

    Our standard immunization program includes both securing polyclonal antiserum and isolation of PBMC for antigen-specific monoclonal VHH-antibody generation. Every new nanobody product we make, has the potential to become a new life-saving drug.

    Our services can offer your R&D everything from PBMC, high-quality RNA and cDNA, to positively screened recombinant antigen-specific nanobodies or VHH from your immunized alpaca.

    • 1st class award-winning animal care on our organic farm

    • Legal ethical approval and approved animal facilities.

    • High-quality laboratory work and robust protocols

    • Quality assurance system in place

    • High IP-security on one-site producing unit

    • No milestones, royalites or licence cost of developed antibodies

    • When you want to develop a monoclonal antibody specific to your target

    • When you want to generate a single-chain antibody specific to your target

    • When you are seeking to develop drug candidates towards your biological target

    • Drug candidate development

    • monoclonal antibody-dependent applications

    • Anti-drug antibody development

    • Custom Antibodies for core research

    • Diagnostic antibody development

    • Immunohistochemistry

    • Neutralizing antibody assay – NAB assay

    • Site-specific antibody development

    • Antigen design – consultation

    • Antigen design by our experts

    • Antigen generation

    • DNA immunization

    • PBMC-isolation & RNA / cDNA extraction

    • Drug candidate generation & drug design

    • Recombinant Antigen-specific Nanobody generation / single-chain VHH generation

What makes us different

  • Capra Science Organic Farm is located in southern Sweden.

    We are proud to say that Swedish authorities have some of the strictest regulations worldwide for animal keeping, ethics and the environment.

    In addition we have chosen to be ISO 9001 as well as organically certified. Our farm is certified organic since many years back and has been awarded multiple times for outstanding animal care.

  • Our top priority is to promote healthy animals with strong immune systems.

    A strong immune system will give substantially higher levels of antigen-specific antibodies in serum upon an antigen challenge. 

  • We have developed unique and gentle immunization programs. The programs are adapted to each host and optimized for a generous production of antigen-specific antibodies.

  • The entire chain of events in antibody production and downstream processes take place onsite. We have a purpose-built organic farm as well as laboratories. We don't work with subcontractors. This guarantees a high level of quality assurance and IP security.

Meet our alpacas

Top 7 reasons to work with us

  1. Expertise. Our advanced laboratory, in-depth knowledge and robust protocols guarantee the best performing antibodies. The antibody expertise of our staff will be within your reach throughout your project.

  2. Discretion. Your project is safe with us. The whole chain of events in your antibody production and downstream processes are done at Capra Science’s own farm and laboratories with no subcontractors.

  3. Quality. Capra Science holds an ISO 9001 quality assurance to guarantee top product quality.

  4. Cost-efficiency. Our unique animal care program has been optimized to yield a high titer antiserum.

  5. Ethical standards. Animal welfare is our top priority. We run 1st class award-winning animal care facilities at our purpose-built organic farm.

  6. Flexibility. Your antibody production is customized to meet your specific needs.

  7. Personal service. A project with us includes free expert email consultation throughout your antibody production. We enjoy the personal contact with every client. Our scientific curiosity and nerdy ambition to continuously learn and improve, make us good listeners and allow us to deliver exactly what you need.